Adenovirus
abm offers an affordable, comprehensive collection of premade adenoviruses containing full-length ORFs for human, mouse, and rat genes for gene over-expression studies. Our standard Adenovirus Collection constructs contain the strong CMV promoter with the option of HA or His tags.
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Adenovirus
We offer genome-wide libraries of siRNA for human, mouse, and rat in a full complement of viral and non-viral delivery systems.
Advantages of the Adenovirus System:
- High transduction efficiency in most mammalian cells
- Low immunogenicity for high post-infection cell viability
- Non-integrating and no risk of disrupting host genes
- Broad host range (dividing, non-dividing, stem cells, and primary cells)
- High titers can be obtained
- Large insert capacity (up to 6 kb)
- A popular choice in vivo and in vitro applications
- Biosafety: abm use replication-incompetent (-E1/-E3) human adenovirus type 5 (Ad5).
Can’t find the adenovirus that you’re looking for? Design your own vector with our Plasmid Planner.
Documents
Top Publications
01
Engulfment of apoptotic cells by macrophages: a role of microRNA-21 in the resolution of wound inflammation.
Das, A., et al.
J Immunol 192(3):1120-9 (2014).
02
Declining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging.
Gomes, A.P., et al.
Cell 155(7):1624-38 (2013).
03
Steroid Receptor Coactivator-2 is a Dual Regulator of Cardiac Transcription Factor Function.
Reineke, E.L., et al.
J. Biol. Chem 289 (25):17721-17731 (2014)
FAQs
What are the recommended storage conditions of recombinant Adenoviruses?
For long-term storage, the virus should be kept at -80°C, especially after CsCl or chromatography purification. At -80°C in 50 mM Tris (pH 7.0) plus 5% glycerol, the viruses could be stable for several years. Alternatively, viral stock could be stored in 10mM Tris (pH 8.0) plus 4% sucrose for in vivo injection as it is more difficult to do in vivo injection with glycerol formulation.
