Primary antibodies are configured to recognize and bind unique regions (epitopes) that can in essence, be presented in the context of a broad range of bio-molecules. The specific nature of the interaction between a primary antibody and its associated epitope has led to the routine application of primary antibodies in the detection/quantification of target molecules in applications such as Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (Flow Cyt), Immunofluorescence (IF), and Immunoprecipitation (IP). As one of the leading suppliers of antibodies worldwide, abm provides >30,000 gene-specific antibodies in addition to the availability of both the monoclonal and polyclonal antibodies from a wide range of host sources (i.e. rabbit, mouse, donkey, goat).
Secondary antibodies are designed to specifically detect the primary antibody, and functions to assist in either the detection, sorting and purification of target antigens. A secondary antibody is specific, both at the species and isotype level, to the relevant primary antibody and usually bears a fluorescent/radioactive/ chemiluminescent or a chromogenic – tag for signal detection and quantification. abm offers a comprehensive selection in regards to species of origin (human, mice, rats, rabbits, sheep, chickens, horses, guinea pigs and more), and a wide array of labelled/conjugated (i.e. Horseradish Peroxidase, biotin, Alkaline Phosphatase and Fluorescein) secondary antibodies with high signal sensitivity and low background.
“I have been using anti-GFP antibodies from your company throughout my entire grad school at the University of Chicago so when I started at Yale I knew from my prior experience that the anti-GFP antibodies from your company are the best from all that I tested and work for various assays with high efficiency and specificity.”
Anna Luchniak, Yale University, Tag Antibody
We offer a wide range of monoclonal and
polyclonal antibodies against a variety
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Gene Transfer Induces Centrosome Amplification and Abnormal Nucleation Associated with Survivin Downregulation in Glioma Cells.
Kurisu, K et al.
Specific domains of FoxD4/5 activate and repress neural transcription factor genes to control the progression of immature neural ectoderm to differentiating neural plate.
Neilson, KM et al.
NMDA receptor function and NMDA receptor-dependent phosphorylation of huntingtin is altered by the endocytic protein HIP1.
Metzler, M et al.
We have been using abm‘s Anti-His Tag Antibody (Mouse Monoclonal) (Cat no. G020) for our western blot experiments, and it worked very well.
University of British Columbia
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SensiStainTM Anti-Nanog Antibody stains for the presence of Nanog, a homeoprotein that functions with pluripotent factors such as Oct4 and Sox2 to maintain embryonic stem cell pluripotency. Expression of nanog has been shown to be present in…
Anti-HGAL Antibody detects for the presence of human germinal center associated lymphoma.
B2 Microglobulin or Beta-2 microglobulin (B2M) is a small membrane protein which can be found almost in all cell surfaces in the body. Particularly, it B2M is shed by the cells into the blood stream (such as B lymphocytes or tumor cells).
Anti-T Cell Antibody recognizes specific T-cell differentiation protein. Has the ability to bind to T cells enabling purfiication of functional T-cells.
Anti-HLA-DR Antibody detects for HLA-DR (Human Leukocyte Antigen – DR isotype), a ligand for the T cell receptor (TCR).
Anti-Thymus-Leukemia Antigen Antibody recognizes leukemia antigen.
Anti-BCA-225 Antibody is a mouse monoclonal, and immunogen used is T47D cell line. May be used to detect the presence of human breast carcinoma associated glycoprotein BCA-225. Predicted size of BCA-225 (220-225kD).
Anti-CD63 Antibody binds detects for CD63, which is a 53kD lysosomal membrane glycoprotein and a member of the tetraspanin family of surface proteins.
Anti-CD13 Antibody detects for CD13 (Aminopeptidase N), which is a type II membrane protein that may be also found in oluble form in cells.
Anti-NGFR Antibody detects for the presence of the NGF Receptor (nerve growth factor receptor).