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Custom Tissue Microarray

Tissue Microarray (TMA) is an innovative tool that allows the simultaneous staining and visualization of multiple samples on the same slide. abm offers custom construction of Tissue Microarrays with a variety of core sizes, and assists with the cutting and staining of Tissue Microarray slides.

We offer the following core sizes with our Tissue Microarray Construction Service:

 

CORE SIZE NUMBER OF ROWS NUMBER OF COLUMNS TOTAL NUMBER OF CORES
2.5 mm 5 8 40
2.0 mm 7 10 70
1.5 mm 10 15 150
1.0 mm 10 17 170

 

“We are happy about the CD4 and CD8 IHC staining your lab did. The quality of the IHC staining is very good.”

Fugang Zhu, Idera Pharnacueticals Inc

Additional Resources:

Service Details

 

Core Services

PRODUCT DESCRIPTION CAT. NO.
Custom Tissue Microarray Construction – Basic Service

Construction of Tissue Microarray block from single tissue blocks provided by the customer.

Customer to provide:

  1. All blocks required to construct the Tissue Microarray. Please contact us if you are not able to provide all blocks required for Tissue Microarray construction.
  2. Indicate the area of interest for each tissue block (please refer to steps 1 and 2 of the workflow for instructions on how to mark your area of interest). Please circle the area of interest on the H&E stained slide and send us the slide and/or the image of the whole slide.

Deliverables: Tissue Microarray Block and report with position information listed for each core.

Lead Time: Project dependent.

Please refer to our Add-On Services below for subsequent services such as: Cutting and Staining.

 HC020
Custom TissueMicroarray Construction – Complete Service

Construction of Tissue Microarray block with single tissue blocks provided by abm. To see list of blocks offered, please contact us with information regarding the tissue types/diseases the customer wishes to include.

Customer to provide:

  1. Information on tissue types/diseases that the customer wishes to include in the tissue microarray and the cores that will be selected from abm‘s FFPE block inventory.

Deliverables: Tissue Microarray Block and report with position information listed for each core, plus donor information for abm supplied blocks, if available.

Lead Time: Project dependent.

Please refer to our Add-On Services below for subsequent services such as: Cutting and Staining.

 HC021

 

 

Add-On Services*

Have the tissue, but can’t embed it or cut it? Don’t worry, send us the tissue sample/block, and we can do the embedding and/or cutting for you!

SERVICE NAME CAT. NO.

Processing of Formalin-Fixed wet tissue suitable for paraffin embedding.

Deliverables: Processed wet tissue suitable for paraffin embedding.

 HC004

Embedding processed tissue into FFPE block suitable for sectioning and subsequent staining.

Deliverables: FFPE tissue block

 HC005

Processing of wet cell pellet into FFPE block suitable for sectioning and subsequent staining.

Deliverables: Paraffin embedded cell pellet block

 HC009

Sectioning of FFPE blocks to produce unstained slides. Unstained slides can be used for H&E, IHC or dye based staining. All slides are cut at 4 μM unless otherwise specified. Please inquire for Tissue Microarray sectioning.

Deliverables: Unstained FFPE tissue section slides.

 HC006

Multiple sections from the same tissue block cut at set distances from one another by the Microtome

Deliverables: Multiple slides cut in sequence by the Microtome from the same specimen.

 HC007

Multiple sections from the same tissue block cut at set distances from one another by the Microtome

Deliverables: Multiple slides within a sample at set distance from one another

 HC008

Digital scans of stained slides at 10X, 20X or 40X magnification. This service is offered in conjunction with IHC, H&E or special staining services.

Deliverables: Digital scan will be digitally provided to the customer.

 HC016
HC017
HC018

Image analysis of stained slides using professional software.

Deliverables: Analysis results will be sent digitally to the client.

 HC011

 

Notes:

*Please note all Add-On Services pricing is subject to ordering with HC001, HC002 or HC003. If ordered as a stand-alone service, pricing is subject to change, please inquire for more details.

#Minimum order of 10 tissue samples is required.

Additional Info

Workflow

Sample Submission Guidelines and Shipping Instructions
To initiate an inquiry, please contact us directly at technical@abmgood.com. Before shipping, please fill out our Custom Tissue Microarray Services Sample Submission Form with your order number and follow the shipping instructions for your samples.

SPECIMEN TYPE SHIPPING INSTRUCTIONS
Unstained slides Place slides in microscope slide boxes. Make sure to seal and wrap the box well.
Formalin-Fixed wet tissues Transfer formalin-fixed sample to 70% alcohol. Seal and wrap the container well to prevent leaks.
Fixed cell pellet Transfer the samples to 70% alcohol. Seal and wrap the container well to prevent leaks.
FFPE tissue blocks Ship tissue blocks in a cassette case or bag. During the month of May to August, ship blocks with gel ice pack to prevent the block from melting due to higher temperatures.

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