CHIR99021
| CAT.NO | UNIT |
|---|---|
| G611 | 2.0 mg |
| SKU | G611 |
|---|---|
| Concentration | 10mM in DMSO (~430ul) |
| Formal Name | 6-((2-((4-(2,4-Dichlorophenyl)-5-(4-methyl-1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)amino)nicotinonitrile |
| Formula | C22H18Cl2N8 |
| Purity | 99% |
| Caution | For Research Use Only, not for therapeutic or diagnostic purposes. |
| Function | Glycogen synthase kinase 3β (GSK3β) inhibitor that has antiproliferative activity in vitro and in vivo. |
| Small Molecule Action | Reprogramming |
| Molecular Weight | 465g/mol |
| Unit quantity | 2.0 mg |
| Stability | 2 years |
| Storage Condition | -20°C |
| Shipping Conditions | On Wet Ice |
| QC | MR and Mass Spectrometry |
Supporting Protocol
MSDS
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- Shen, J., Lyu, C., Zhu, Y., Feng, Z., Zhang, S., Hoyle, D. L., … Wang, Z. Z. "Defining early hematopoietic‐fated primitive streak specification of human pluripotent stem cells by the orchestrated balance of Wnt, activin, and BMP signaling" Journal of Cellular Physiology 234(9):16136–16147 (2019). DOI: 10.1002/jcp.28272.
