August 2022 / NEWSLETTER

PRODUCT SPOTLIGHT

Say Goodbye to linear RNA with RNase R

 abm's RNase R is an E.coli exoribonuclease that efficiently digests nearly all linear RNA species. This enzyme is ideally suited to the study of lariat RNA produced by traditional splicing, as well as circRNAs which arise through back-splicing. By removing linear RNAs from cellular or RNA extracts, RNase R greatly facilitates the identification of circular species through RNA-sequencing. This enables researchers to probe the landscape of splicing events with greater depth.

Enzyme Features:

• Enriching circRNAs in biological samples
• Identification of intronic lariat sequences
• Identification of exonic circRNAs
• Studying alternative splicing
• Production of artificial circular RNAs

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NEW PROMOTION

New and Improved: MegaFi Pro Fidelity Polymerase

 We've elevated PCR performance with a new formulation. Feel more confident with 2000X reduction in error rates with 3X the affordability!

This strategically-engineered polymerase (Cat. No. G886) is partnered with a monoclonal antibody which inhibits 5’ → 3’ polymerase activity and 3’ → 5’ exonuclease activity, allowing for highly specific Hot Start reactions. This high fidelity polymerase is perfect for Next Generation Sequencing, molecular cloning, or diagnostics. 

Enzyme Features:

• 2000X lower error rate than regular Taq
• Suitable for difficult templates 
• MegaFi^TM Pro Fidelity 2X PCR MasterMix available (Cat. No. G887)

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